产品货号：
Z11627
中文名称：
Artemis/DCLRE1C抗体
英文名称：
Anti-Artemis/DCLRE1C Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Artemis/DCLRE1C Antibody |
| 指标别名 | A SCID;ARTEMIS;ASCID;DCLRE1C;DCLREC1C;hSNM1C;Protein A SCID;Protein artemis;RS SCID;SCIDA;SNM1 homolog C;SNM1 like protein;SNM1C |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC,WB |
| 基因名称 | DCLRE1C |
| 抗体来源 | Goat |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding an internal region of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C). |
| 计算分子量 | 78kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.This antibody detects a band of the appropriate size in a number of different cell lines.However,it does not detect a band in cell lines that do not express artemis,such as the cell line CJ (see figure) and in an hTERT line (not shown). |
| 浓度 | 1.2mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair.DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining. |
| Uniprot ID | Q96SD1 |
| 基因名全称 | Protein artemis |
| 推荐稀释比 | ELISA:1:10,000 - 1:20,000 IHC:1:1,000 WB:1:500 - 1:2,000 |
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